AIM: To summarize and analyze the results of neonatal eye screening using digital wide-area fundus imaging system(RetCam3)in general hospital, and to provide references for the prevention and treatment of neonatal eye diseases.

METHODS: There were 7 239 newborns subjected to eye examinations in Zhongshan City People's Hospital from December 2018 to December 2021, and RetCam3 was used to obtain eye screening images. Newborns with abnormal screening results were treated and followed up accordingly.

RESULTS: Among 7 239 newborns, 1 200(16.58%)newborns were diagnosed with abnormal eyes, including 7 cases of anterior segment abnormalities and 1 193 cases of fundus abnormalities. Among 7 cases of anterior segment abnormalities, 2 cases were congenital cataract, 2 cases were pupillary residual membrane, and 3 cases were corneal leukoplakia. Among 1 193 cases of fundus abnormalities, 1 141 cases were retinal hemorrhage(RH), and 19 cases were retinopathy of prematurity(ROP). In addition, there were 6 cases of ROP-like in term infants.

CONCLUSION: Neonatal ocular abnormalities mainly develop in the posterior segment of the eye. Neonatal eye disease screening in general hospitals is beneficial to early detection and treatment of neonatal ocular diseases.