目的：观察有晶状体眼后房屈光晶状体(PC-PRL)植入术治疗超高度近视的临床疗效。

方法：回顾性病例研究。选取2021-01/2022-01于我院行PC-PRL植入术治疗的超高度近视患者36例67眼，按术前球镜度数分成两组：球镜≤-18.00D者16例30眼和球镜>-18.00D 者20例37眼。比较两组患者手术前后视力、眼压、角膜内皮细胞密度(ECD)、中央前房深度(ACD)以及术后拱高、并发症的情况。

结果：两组患者术后3mo UCVA均达到或超过术前BCVA(均P<0.05)，且球镜>-18.00D组的视力提高幅度更大(P<0.01)； 两组患者术后1d眼压、角膜内皮细胞密度与术前比较均有差异(均P<0.05)； 术后不同时间点拱高均呈下降趋势，但均在正常范围内； 术后3mo ACD均低于术前(均P<0.01)。两组间手术前后眼压、ECD、ACD及术后拱高比较均无差异(P>0.05)。两组患者术后均未发生严重并发症。

结论：PC-PRL植入术治疗超高度近视患者早期视力得到良好改善、屈光状态稳定、安全可靠、无严重并发症。

METHODS: Retrospective case study. A total of 36 patients(67 eyes)with ultra-high myopia who underwent PC-PRL implantation in our hospital from January 2021 to January 2022 were selected. They were and divided into two groups according to the preoperative spherical equivalent, with 16 cases(30 eyes)in spherical equivalent ≤-18.00D group and 20 cases(37 eyes)in spherical equivalent >-18.00D group. The preoperative and postoperative visual acuity, intraocular pressure(IOP), corneal endothelial cell density(ECD), central anterior chamber depth(ACD)and postoperative vault and complications were compared and analyzed.

RESULTS: The uncorrected visual acuity(UCVA)at 3mo after operation of the two groups reached or exceeded the preoperative best corrected visual acuity(BCVA; all P<0.05), and the spherical equivalent >-18.00D group had a greater visual acuity improvement(P<0.01). There were significant differences in IOP and corneal ECD between the two groups at 1d after operation and before operation(all P<0.05); The vault at different time points decreased after operation, but it was within the normal range; The ACD at 3mo after operation was lower than that before operation(all P<0.01). There was no difference in intraocular pressure, ECD, ACD and postoperative vault between the two groups(P>0.05). No serious postoperative complications occurred in both groups.

CONCLUSION: The PC-PRL implantation had improved early visual acuity and stable refractive state, which was safe and reliable, and there were no serious complications in the treatment of patients with ultra-high myopia.