目的：探讨特发性黄斑前膜(IMEM)患者手术前后黄斑区微结构与术后视功能恢复的相关性。

方法：选取2017-01/2019-12就诊于我院的IMEM患者43例43眼，术前、术后3、6、9mo均检测最佳矫正视力(BCVA)，进行视物变形(M-chart评分表)评分，并采用频域光学相干断层扫描(SD-OCT)测量中心凹视网膜厚度(CFT)、中心凹下脉络膜厚度(SFCT)、神经节细胞-内丛状层(GC-IPL)厚度及嵌合体(IZ)带缺损长度。

结果：术后3、6、9mo，纳入患者BCVA和视物变形程度均较术前逐渐改善(均P<0.05)，且BCVA与CFT、IZ带缺损长度均呈正相关(P<0.05)，与SFCT、GC-IPL厚度均无相关性(P>0.05)； 视物变形评分与CFT均呈正相关(P<0.05)，与SFCT、GC-IPL厚度、IZ带缺损长度均无相关性(P>0.05)。

结论：CFT和IZ带缺损长度与IMEM术后BCVA具有显著相关性，这两项指标可作为预测IMEM术后视功能恢复的指标。

METHODS: A total of 43 patients(43 eyes)with IMEM who were treated in our hospital between January 2017 and December 2019 were selected. The best corrected visual acuity(BCVA)of each patient was examined preoperatively and at 3, 6, 9mo after surgery. Moreover, metamorphopsia(M-chart)examination was given, and spectral domain-optical coherence tomography(SD-OCT)was used to measure central foveal thickness(CFT), subfoveal choroidal thickness(SFCT), the thickness of ganglion cells-inner plexiform layer(GC-IPL)and the length of interdigitation zone(IZ)defect.

RESULTS: The BCVA and the metamorphopsia were gradually improved at postoperative 3, 6 and 9 mo(all P<0.05). Moreover, the BCVA was positively correlated with CFT and the length of the IZ defect(P<0.05), while it was not correlated with SFCT and the thickness of GC-IPL(P>0.05). The metamorphopsia assessment was positively correlated with the CFT at postoperative 3, 6, and 9mo(P<0.05), while it was not correlated with SFCT, the thickness of GC-IPL and the length of IZ defect(P>0.05).

CONCLUSIONS: The CFT and the length of IZ defect were significantly correlated with the BCVA after IMEM surgery, which can be used as indicators to predict the recovery of visual function after IMEM surgery.