Affiliated Hospital of Binzhou Medical University
As a highly prevalent global condition, myopia significantly impacts the ocular health of young individuals in China. Orthokeratology lens, as rigid corneal contact lens, has demonstrated effective control over the progression of myopia; however, its precise mechanism of action remains incompletely elucidated. Higher-order aberrations, which are significant determinant of visual quality, undergo marked changes following Orthokeratology, with particular emphasis on the alterations in spherical aberrations and coma. The change in corneal morphology induced by Orthokeratology lead to significant positive increase in both spherical aberration and coma. Furthermore, the observed elevation of spherical aberration and coma demonstrates a negative correlation with the rate of axial length growth following Orthokeratology. The interplay among spherical aberration, coma, defocus, accommodation, astigmatism, and pseudo-accommodation may constitute the underlying mechanism governing the control of myopia through Orthokeratology.