目的：探讨急性原发性闭角型青光眼(APACG)首次发作后1a内视盘周围脉络膜厚度(pCT)的变化规律。

方法：前瞻性队列研究。选取2015-10/2019-09于石家庄市人民医院眼科诊治的APACG患者31例(发作眼组31眼，对侧临床前期眼组31眼)，正常对照组30例30眼，三组均在APACG发作期，术后1wk，1、3、6mo，1a测量pCT。

结果：发作眼组pCT在术后1wk时比发作期增厚，之后1a内持续变薄(P<0.05)。发作眼组pCT较其余两组：在发作期，术后1wk时增厚，1a时变薄(P<0.05)。发作眼组发作期平均pCT与高眼压持续时间正相关，与前房深度负相关(P<0.05)。

结论：首次发作的APACG患者，pCT在发作期和术后1wk弥漫增厚，1mo恢复正常，1a时变薄。发作期平均pCT与高眼压持续时间正相关，脉络膜厚度在APACG的发作中可能有重要作用。

METHODS: A prospective cohort study. A total of 31 patients with APACG who admitted to the ophthalmology department of Shijiazhuang People's Hospital from October 2015 to September 2019 were selected, with 31 eyes in attack group, 31 fellow eyes in preclinical group and 30 cases(30 eyes)in control group. pCT of the three groups was measured respectively at the attack period, 1wk, 1, 3, 6mo and 1a after surgery.

RESULTS: The pCT of the attack group was thicker than that in the attack period when at 1wk after surgery, and continued to become thinner within the following 1a(P<0.05). The pCT of the attack group was thicker than that of the other two groups during the attack period and at 1wk after surgery, while it became thinner at 1a(P<0.05). In the attack group, the average pCT was positively correlated with the duration of intraocular hypertension and negatively correlated with the anterior chamber depth(P<0.05).

CONCLUSION: For patients with first episode of APACG, pCT was diffusely thickened during attack and at 1wk after surgery. The pCT returned to normal at 1mo, while it became thinner at 1a. Furthermore, the average pCT was positively correlated with the duration of intraocular hypertension, and the choroidal thickness may play an important role in the attack of APACG.