目的：评价选择性激光小梁成形术(SLT)治疗原发性开角型青光眼(POAG)的临床效果。

方法：回顾性研究。纳入2022年6月至2023年12月在我院就诊的药物治疗眼压控制不佳的POAG患者24例33眼，均行SLT治疗。比较治疗前后眼压变化、视野范围指数[视野平均缺损(MD)及缺损程度平均敏感度(MS)]变化、视盘周神经厚度及其血流密度(VD)变化。

结果：治疗后1、3、6、12 mo患者眼压较治疗前均有明显下降(均P<0.001)。MD值及MS值在治疗前，治疗后6、12 mo时比较无差异(均P>0.05)； 治疗后12 mo视盘周围神经厚度及血流密度较治疗前无差异(均P>0.05)。

结论：SLT短期内对POAG患者能够显著降低眼压，且对视野及视盘周围神经无损害，但SLT的有效性随时间延长而下降。

METHODS:Totally 24 patients(33 eyes)with POAG who had poor control of intraocular pressure(IOP)from June 2022 to December 2023 were included in this retrospective study, and all of them were treated with SLT. Furthermore, the IOP, mean deviation(MD), mean sensitivity(MS), and the thickness and vascular density(VD)of optic disc nerve layer were compared after treatment.

RESULTS: There were significant reducion in IOP at 1, 3, 6, 12 mo after treatment(all P<0.001). There were no statistically significant differences in MD and MS before treatment and at 6 and 12 mo after treatment(all P>0.05), and there were no statistical significant differences in the thickness and VD of optic disc(all P>0.05).

CONCLUSION: SLT can significantly reduce IOP in POAG patients in the short term, without damaging the visual field and optic disc nerves, while the effectiveness of SLT decreases over time.