目的：观察和分析多区正向设计离焦(DIMS)与角膜塑形镜控制青少年近视眼轴长度(AL)增长的临床效果。

方法：选取2021年4月至2023年4月就诊于本院的青少年近视患者120例120眼(取主视眼数据进行研究)进行回顾性研究。根据患者选择意愿分为DIMS组和角膜塑形镜组，各60例60眼。随访1 a，比较两组患者配戴前后等效球镜度(SER)、AL变化情况。

结果：两组青少年一般资料具有可比性。两组患者戴镜前后SER比较有差异(F_时间=123.700，P_时间<0.001； F_组间=7.499，P_组间=0.007； F_交互=3.580，P_交互=0.029)。两组患者戴镜前后AL比较时间交互作用有差异(F_时间=40.100，P_时间<0.001； F_交互=5.830，P_交互=0.003)，组间无差异(F_组间=0.008，P_组间=0.927)。戴镜后6 mo，1 a，两组青少年SER、AL变化量比较有差异(均P<0.01)，其中角膜塑形镜组SER、AL变化量小于DIMS组。

结论：相较于DIMS，角膜塑形镜对近视青少年AL增长的控制效果较好。

METHODS: A retrospective study was conducted on 120 adolescent myopia patients(120 eyes)who visited our hospital from April 2021 to April 2023(using data from the main eye for study). According to the patient's preference, they were divided into DIMS group and orthokeratology group, with 60 cases(60 eyes)in each group. Followed-up for 1 a, the changes in spherical equivalent refraction(SER)and AL before and after wearing lenses were measured.

RESULTS: The general data of adolescents in the two groups were comparable. There were significant differences between two groups in SER before and after wearing glasses(F_time=123.700, P_time<0.001; F_group=7.499, P_group=0.007; F_interaction=3.580, P_interaction=0.029). The difference of AL between the two groups in comparison of time and interaction before and after wearing glasses was statistically significant(F_time=40.100, P_time<0.001; F_interaction=5.830, P_interaction=0.003), there was no statistically significant difference between groups(F_group=0.008, P_group=0.927). After wearing lenses for 6 mo and 1 a, there was a statistical difference between the two groups in the changes of SER and AL(all P<0.01). Among them, the changes in SER and AL in the orthokeratology lenses group were smaller than those in the DIMS group.

CONCLUSION: The orthokeratology lenses have a better effect than the DIMS on controlling the AL growth in myopic adolescents.