两种小梁切除术治疗原发性青光眼疗效对比研究
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A contrastive study of efficacy between two kinds of trabeculectomy in primary glaucoma
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    摘要:

    目的:对比分析两种小梁切除术对青光眼的疗效。

    方法: 将我院选择2006-05/2011-09青光眼患者300例384眼随机分为观察组160例200眼与对照组140例184眼,分别行复合式小梁切除术及传统小梁切除术,比较两组手术疗效,并随访1a。

    结果:所有手术均顺利完成。术后1wk观察组(复合式小梁切除术)和对照组(传统小梁切除术)浅前房发生率分别为7.5%和21.7%差异有统计学意义(P<0.05)。术后1a观察组手术成功率为90.0%明显高与对照组的65.2%(P<0.05); 术后 1a,观察组和对照组功能性滤泡形成率分别为86.0% 和63.0%,经比较差异有统计意义(P<0.05); 观察组术后并发症发生率明显低于对照组(P<0.05)。

    结论:复合式小梁切除术较传统小梁切除术治疗青光眼疗效确切,能有效减少术后浅前房的发生,功能性滤过泡形成和远期手术成功率方面疗效显著,且并发症低,适用于临床推广。

    Abstract:

    AIM: To analysis the curative effect of two kinds of trabeculectomy for glaucoma.

    METHODS: Totally 300 cases(384 eyes)of glaucoma patients in our hospital from May, 2006 to September, 2011 were randomly divided into observation group 160 cases(200 eyes)and control group 140 cases(184 eyes), treated with combined trabeculectomy and traditional trabeculectomy, respectively. Two groups of curative effect were compared, and they were followed up for 1y.

    RESULTS: All operations are completed smoothly. At postoperative 1wk, observation group(combined trabeculectomy)and control group(traditional trabeculectomy)in incidence of shallow anterior chamber were 7.5% and 21.7%. The difference was statistically significant(P<0.05). Surgical success rate was 90.0% after 1y in observation group which was obviously higher than 65.2% in the control group(P<0.05); one year postoperatively, functional follicular formation rate of the observation group and the control group were 86.0% and 63.0%, respectively, and the differences had statistical significance(P<0.05); the incidence of postoperative complications of observation group was obviously lower than that in the control group(P<0.05).

    CONCLUSION: Combined trabeculectomy for glaucoma receives better curative effect than that of traditional trabeculectomy, and can effectively reduce the occurrence of postoperative shallow anterior chamber, the functional filtering bleb formation as well as long-term success rate of surgery is distinct, and complication is low. Thus, it is suitable for clinical promotion.

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王静,蒋莹,文玉民,等.两种小梁切除术治疗原发性青光眼疗效对比研究.国际眼科杂志, 2014,14(5):819-821.

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  • 收稿日期:2014-02-27
  • 最后修改日期:2014-04-04
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  • 在线发布日期: 2014-04-21
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