AIM: To investigate the changes of early anterior chamber parameters after femtosecond laser in-situ keratomileusis(FS-LASIK).

METHODS:A total of 90 patients(90 eyes)in routine operation indications received FS-LASIK operation from January to June 2014 in our hospital were collected, including 47 males(47 eyes), 43 females(43 eyes), aged 18-33 years old(mean age 22.38±3.96 years). According to the diopter, the patients were divided into three groups: 30 cases(30 eyes)were in mild myopia group(group A)with diopter ≤3D; 30 cases(30 eyes)were in moderate myopia group(group B)with diopter >3D and ≤6D; 30 cases(30 eyes)were in high myopia group(group C)with diopter >6D. Pentacam measurements were used to measure the anterior chamber parameters including the changes of anterior chamber depth(ACD), anterior chamber volume(ACV), anterior chamber angle(ACA)before surgery and at 1, 3mo after surgery respectively.

RESULTS:All surgical procedures were performed successfully without complications. Compared with the value of ACD and ACV at pre-operation and 1, 3mo post-operation among groups A, B, C, there was statistically significant difference(P<0.05). In group A, there was statistically significant difference between the values of ACD, ACV at 1, 3mo post-operation(P<0.05), while in groups B, C, there was no statistically significant difference(P>0.05). However, in groups A, B and C, the value of ACA had no statistically significant difference(P>0.05). Diopter had no obvious relevance with the changes of ACD, ACV, ACA values.

CONCLUSION:The early changes of anterior chamber parameters after FS-LASIK, including that ACD become shallow, ACV become smaller, but there was no obvious effect on the peripheral anterior chamber angle. There will be a further instruction for those people who want to perform intraocular surgery after ocular refractive surgery.