AIM: To provide a reference for the selection of surgical methods for the clinical treatment of blepharophimosis-ptosis-epicanthus inversus syndrome by analyzing the efficacy and patient satisfaction of congenital blepharoplasty patients.

METHODS: A retrospective analysis of blepharophimosis-ptosis-epicanthus inversus syndrome staging surgeries included 23 cases(46 eyes), in which 6 patients(12 eyes)had family history, 2 patients(4 eyes)of strabismus, 1 patients(2 eyes)of nystagmus. First-stage surgery of “Y-V” plasty and Ammon canthoplasty were performed at average age of 5±1.9; second-stage surgery of frontal muscle flap suspension were performed at average age of 6±2.7. Postoperative follow-up lasted for 12mo. We evaluated and analyzed the efficacy, asked the patients to give the score to the surgeries.

RESULTS: Palpebral fissure length(PFL)was extended from 17.83±3.1mm in the right eye and 17.87±2.9mm in the left eye to 23.59±1.7mm and 23.59±1.8mm after surgeries. The palpebral fissure height(PFH)was increased from 2.91±1.4mm in the right eye and 2.91±1.2mm in the left eye to 7.89±0.9mm in the right eye and 7.89±0.7mm in the left eye after surgeries. The length of epicanthus was reduced from 18.7±2.1mm to 7.8±1.8mm after surgeries. The width of epicanthus was reduced from 3.9±0.8mm before surgeries to 1.3±0.8mm after surgeries. The inner canthal spacing(IICD)was shortened from 37.70±3.3mm before surgeries to 30.70±2.6mm after surgeries. The distance from the upper eyelid margin of the corneal reflector to the upper eyelid(MRD1)increased from -1.67±1.6mm of the right eye before surgery, and -1.80±1.6mm of the left eye to the postoperative +3.35±0.7mm in the right eye and +3.35±0.6mm in the left eye. IICD/PFL decreased from 2.1±0.2 to 1.3±0.4 postoperatively. The satisfaction score was 47±2.1(full score was 60), and the patient was more satisfied with the curative effect and postoperative beauty.

CONCLUSION: The surgical treatments of blepharophimosis-ptosis-epicanthus inversus syndrome can be divided into the first-stage of “Y-V” plasty and Ammon lateral canthoplasty and the second-stage frontal muscle flap, which can get satisfaction of the patients.