AIM: To explore the effect of fundus laser combined with Qi Ming granule on diabetic retinopathy in stage Ⅲ.

METHODS: Fifty six patients with Ⅲ stage diabetic retinopathy who were treated in our hospital from December 2017 to June 2018 were divided into control group(28 cases)and observation group(28 cases)according to the treatment method. The control group was treated with panretinal photocoagulation. The observation group was treated with Qi Ming granule combined with retinal laser photocoagulation. The best-corrected visual acuity(BCVA), mean defect of visual field(MD), and central macular thickness(CMT)were examined before photocoagulation and 1mo, 3mo and 6mo after photocoagulation to compare the retinal function between the two groups.

RESULTS: The mean BCVA, MD and CMT values of the eyes in the PRP+ drug treatment group and the PRP treatment group were statistically significant(P<0.05)at 1, 3, and 6mo after treatment. The mean BCVA, MD and CMT values between the two groups were statistically significant(P<0.05)at 1 and 3mo after treatment. There was no significant difference at 6mo after treatment(P>0.05).

CONCLUSION: Qi Ming granule can alleviate the degree of laser photocoagulation damage to the retina, promote the rapid repair of laser damage, and reduce diabetic macular edema. It is worthy of popularization and application in the clinic.