AIM: To evaluate the efficacy, predictability and safety of surgical respositioning of in-the-bag intraocular lens dislocated into the vitreous cavity.

METHODS: A retrospective case control study was adopted to analyze 8 eyes of 8 patients with spontaneous in-the-bag intraocular lens dislocated into the vitreous cavity. The study was conducted from April 2017 to June 2019. 8 eyes of 8 patients who had undergone standard 23G pars plana vitrectomy and in-the-bag intraocular lens were respositioned by ciliary sutures fixed act as research group.10 eyes of 10 patients with lens dislocated into vitreous cavity, which were performed with phacofragmentation and ciliary sutures fixed during the same period act as the control group. Patients were examined 7, 30 and 60d postoperatively. The examinations included uncorrected visual acuity, best corrected visual acuity, intraocular pressure, corneal astigmatism, the tilt and decentration of the IOL, complacations of surgeries etc.

RESULTS: Successful IOL implantations were achieved in all eyes. Visual acuity: At 7, 30, and 60d after surgery, the uncorrected visual acuity of the two groups was both improved compared with before surgery, and the difference was statistically significant(P<0.05). There was no difference between the best corrected visual at 7, 30, 60d after surgery and before(P>0.05). There was no difference in uncorrected visual acuity between the two groups, but there was statistically significant difference in uncorrected visual acuity between 7d and 30d, 7d and 60d after operation(P<0.001). There was no significant difference in corrected visual acuity between the two groups at 7d, 30d and 60d after operation(P>0.05). Intraocular pressure: Intraocular pressure in the two groups was within the normal range(10mmHg-21mmHg)at 7, 30 and 60d after surgery, and there was no statistically significant difference between the groups(P>0.05), while the difference between the groups was not statistically significant. Corneal astigmatism: At 30d after surgery, the corneal astigmatism of the two groups was both increased than before, at 60d after surgery, the corneal astigmatism of the control group was increased than before, and the differences were statistically significant(P<0.05). The corneal astigmatism of research group at 30 and 60d after surgery was significantly lower than control group(P<0.05). The tilt and decentration of the IOL: The tilt and decentration of the IOL of research group at 30 and 60d after surgery was significantly lower than control group(P<0.05).

CONCLUSION: Surgical respositioning of spontaneous in-the-bag intraocular lens dislocated into the vitreous cavity provides efficacy and predictability and is safe and reliable.