AIM: To evaluate the efficacy evaluation of the combined application of bandage contact lens after pterygium excision surgery by Meta-analysis.

METHODS: Randomized controlled clinical studies on combined application of corneal bandage contact lens after pterygium excision were retrieved from PubMed, Cochrane Library, Wanfang, VIP, CNKI and other databases from May 2014 to May 2020. Data were extracted and Meta-analysis was performed.

RESULTS:Totally 11 randomized controlled clinical studies were included, including 10 in Chinese and 1 in English, with 864 patients. Meta-analysis results showed that 1d postoperative \〖MD= -1.57, 95%CI=(-1.72, -1.41), P<0.00001\〗, 2d postoperative \〖MD= -1.35, 95%CI=(-1.59, -1.11), P<0.00001\〗, 7d postoperative \〖MD= -0.64, 95%CI=(-0.78, -0.50), P<0.00001\〗 combined application of corneal bandage contact lens can better reduce the degree of ocular pain in patients; And 1d postoperative \〖MD= -1.23, 95%CI=(-1.51, -0.95), P<0.00001\〗, 7d postoperative\〖MD= -0.44, 95%CI=(-0.50, -0.39), P<0.00001\〗 combined application of corneal bandage contact lens can better promote the condition of corneal epithelium.

CONCLUSION:The bandage contact lens could markedly release pain response after pterygium excision surgery, promote corneal epithelium recovery, which is beneficial to reduce the symptoms of clinical discomfort.