AIM:To explore the correlated factors between multivariate ocular factors and the development of dry eye.·METHODS:Five hundred and thirty-six cases with dry eye were selected and evaluated with a series of ocular testing of the Schirmer test,the tears film stability,the staining with fluorescein sodium on cornea.A question-naire about dry eye was surveyed.The multivariate non-conditional Logistic regression analysis was used to analyze the relation between multivariate ocular factors and the development of dry eye.·RESULTS:The Logistic regression predictive equation for dry eye was:Y=-2.21+0.459 X3+10.572 X4-0.069 X5+0.766 X6+0.924 X7+0.264 X9-1.78 X12+7.235 X13+4.917 X14+5.148 X15;P=exp(Y)/[1+exp(Y)].The P value meant the probability of suffering dry eye.·CONCLUSION:Our data showed that multivariate ocular factors might play a role in the development of dry eye.The clinical features of dry eye are significant for the diagnosis,and it can be predicted by using the suitable logistic predictable equation.