To evaluate the clinical effect of the lacrimal canalicular anastomosis by using topic anesthetics under microscope. METHODS: The medial broken ends of the disrupted canaliculi of 21 cases 21 eyes were researched under microscope,and by using topic anesthetics, epidural catheters were used as supports for anastomosis. RESULTS: The anastomos was successful in 19 cases 19 eyes, and improved in 2 cases 2 eyes. CONCLUSION: All 21 cases of anastomosis were succeeded in the first time of operation, extubation was done 812 weeks postoperatively, and the followup ranged 624 months. The lacrimal canalicular anastomosis is safe and effective by using topic anesthetics, and the clinical effect of the operation is good and worthy of being spread.