·AIM:To evaluate the safety and efficacy of sub-bleb bevacizumab injection in treatment of filtering bleb neovascularization.·METHODS:A group of treament cases of filtering bleb by injecting bevacizumab 1mg(0.04mL,25mg/mL)were retrospectively analyzed.All the cases,8 cases of 8 eyes,were followed-up for 2-6 months.·RESULTS:Two weeks after the injection,intraocular pressure dropped to normal in 87.5%,neovascularization of bleb disappeared in 87.5%.All the cases had not such symptoms as high intraocular pressure,uveitis,adverse reaction of inner eyes or the whole body.·CONCLUSION:The sub-bleb injection of bevacizumab is an ideal choice to inhibit the neovascularization.It is easy to operate with fewer complications.It can be more effective if used earlier.However,it still needs further large sample multicentre clinical research.·