·AIM:To evaluate the clinical effect of lacrimal duct flush with an improved method in treating neonatal dacryocystitis.·METHODS:Two hundred and eighty cases(340 eyes)with neonatal dacryocystitis were treated with lacrimal duct flush between 2006 and 2009,the cases were grouped in two categories:140 cases 164 eyes in A(lacrimal duct flush)group,and 140 cases 176 eyes in B(lacrimal duct flush with an improved method)group.·RESULTS:After follow-up for 3-18 months,141 eyes 86.0% of 164 eyes were not cured by lacrimal duct flush in A group.However,there were only 17 eyes 9.7% of 176 eyes need probing in B group.·CONCLUSION:Lacrimal duct flush with an improved method is an effective method in treating neonatal dacryocystitis.·