AIM: To investigate the factors correlated with central corneal thickness(CCT) in patients with myopia. METHODS: A total of 2 027 patients 4 002 eyes of myopia were examined. CCT was measured by ultrasound corneal pachymeter. Refraction was measured by automatic refractor. Intraocular pressure (IOP) was mea-sured by non-contact tonometer. Corneal endothelia was measured by corneal topography. History of wearing soft contact lens and other factors were also analyzed. RESULTS: A negative correlation was found between CCT and history of wearing soft contact lens (t=- 4.475, P=0.000).The correlation between IOP and CCT was significant (r=2.856, P=0.000), and. CCT was nega-tively correlated with refraction (r=- 0.662, P=0.000). No signifi-cant correlation was found between CCT and corneal endothelia. CONCLUSION: The CCT in patients of myopia was correlated with history of wearing soft contact lens,refraction and IOP.