AIM: To observe the therapeutic effect of posterior scleral reinforcement operation on degenerative myopia. METHODS: Comparative observation on the changes of 52 cases (83 eyes) in visual acuity and axis of the eyeball was performed after 6 to 11 years’ follow-up. RESULTS: Visual acuity of all cases was significantly improved at different degrees (P<0.01). After 6 to 11 years’ follow-up, the average increased eyeball axis was 0.08, 0.10 and 0.13mm. The increased eye diopter was lower than 0.5D each year postoperatively. CONCLUSION: Posterior scleral reinforcement surgery can elevate visual acuity, delay and control the progres-sion of myopia, as well as decrease the complication of myopia. The posterior scleral reinforcement operation currently is an effective method in treatment of degene-rative myopia.