·AIM:To observe clinical effect and safety of manual small incision cataract surgery on cataract with high myopia.·METHODS:A total of 78 eyes of 61 patients received manual small incision cataract surgery with low-degree and large-diameter intraocular lens implantation.The postoperative visual acuity,refractive status,and surgical complications were observed.Patients were followed up 6 to 24 months after operation.·RESULTS:A total of 78 eyes were successfully implanted in intraocular lens.Their visual acuity improved to varied degrees.The best corrected visual acuity of 2 eyes were<0.1 at 3 months after operation,twenty-six eyes were between 0.1 and 0.4,fifty eyes were>0.4.The majority of patients remained a low degree of residual myopia refractive state.Twelve eyes suffered from posterior capsular opacification.Anterior capsule tear and posterior capsule rupture or other complications did not happen during surgery.There was no retinal detachment or cystoid macular edema.·CONCLUSION:Manual small incision cataract surgery with low-degree and large-diameter intraocular lens implantation has advantages such as good clinical effect,high operative security and fewer complications.In the regions where economic conditions are relatively backward,it is worthy of popularization.·