·Retinopathy of prematurity(ROP)is retinal vascular proliferative lesion occurred in prematurity and low birth weight infants.With the rising of the survival rate of premature children in recent years,the incidence of ROP has increased significantly.ROP treatment in the threshold or late threshold period is mainly the retinal laser and surgical treatment,while giving the body systemic hormone drugs.Due to the late timing of treatment,high surgical risks and many complications,the treatment effect is not ideal.To explore a simple,safe and effective treatment method has become the consensus of researchers in the early lesions stage.We reviewed the new progress on the current treatment of ROP.·