Abstract:·AIM:To observe the corneal endothelial cells morpho-logy after phacoemulsification,and find out the regularity of corneal endothelial cells morphologic change and some related influencing factors.·METHODS:Seventy-nine cases 91 eyes with age-related cataract were chosen in this research.The phacoemul-sification was performed through the clear cornea combined with the foldable intraocular lens implantation.The cell density(CD),coefficient of variation(CV)of the endothelial cells in the central and incision cornea were examined preoperatively and 3 days postoperatively.·RESULTS:The level of postoperative CD decreased gradually,and the level of CV increased.Morphology of endothelial cells in the incision cornea showed a significant lower CD,higher CV than those in the central cornea at 3 days postoperatively.·CONCLUSION:In phacoemulsification through the clear cornea,the endothelial cells suffer from energy and mechanic injury.The corneal endothelial cells in incision are easier to be damaged than that in the central part during this surgery,We should pay more attention to the mechanic injury in elder patient,because it lead to more corneal endothelial cell loss.·