AIM:To investigate medical treatment and nursing of neovascular glaucoma(NVG) patients treated by intravitreous injection of Avastin combined with trabeculectomy and mitomycin C(MMC).METHODS: Twenty-four patients with angle-closure NVG were treated by intravitreous injection of Avastin combined with trabeculectomy and MMC. Psychological nursing was offered which could eliminate tention and fear of patients, build their confidence of conquering disease. Meanwhile, preoperative nursing, postopreative nursing as well as health guidances were also provided.RESULTS:Stable psychological situations were achieved in all patients which cooperated with medical treatment and nursing well, general NVG nursing knowledges and skills were acquired at the same time.CONCLUSION:Intravitreous injection of Avastin combined with trabeculectomy and MMC is effective on NVG treatment,which also brings new problem for nursing. Successful operations are guaranteed by psychological nursing and preoperative guidances, postopreative careful observation on visual situations as well as health guidances.