AIM:To observe the effect of tamponade of silicone oil on central corneal thickness after different retinal surgeries.METHODS:According to the degree of diseases,37 patients 40 eyes underwent different surgeries:simple vitrectomy 14 eyes,vitrectomy with tamponade of silicone oil 15 eyes,vitrectomy and lensectomy with tamponade of silicone oil 11 eyes.With A-mode ultrasonic apparatus,central corneal thickness was measured preoperatiuely and 1 week,1 month,3 months and 6 months postoperatively.RESULTS:In all three groups,central corneal thickness had increased at different degrees.Compared with the central corneal thickness of preoperation,that of 1 week postoperatively had significant differences in all 3 groups.The central corneal thickness came to the same degree 1 week,1 month,3 months and 6 months postoperatively as that of preoperation in first and second group,while compared with the central corneal thickness of preoperation,that of 6 months postoperatively had a obviously significant difference in the third groups.CONCLUSION:In the circumstances of well-controlled intraocular pressure,vitrectomy with tamponade of silicone oil have no obvious effect on central corneal thickness while vitrectomy and lensectomy with tamponade of silicone oil can significantly increase the central corneal thickness 6 months postoperatively.