The hemostatic biological glue (fibrin sealant) is biological adhesive with a human blood or animal blood fibrinogen as materials,which can stop bleeding by the simulation of human clotting process with the organi-zation hemostatic effect.Biological glue have many advantages such as natural closed,quick and good healing and quickly absorption.Till now,it has been widely applied in the eye surgery area,Comparative study showed that the comfort,convenience and safety of biological adhesive are better than suture surgery,this paper was a literature review.about biological glue in ocular application.