· AIM:To evaluate the clinical effect of anterior chamber puncture and pH determination in the treatment of moderate ocular alkali burns.· METHODS:Totally 78 patients of moderate ocular alkali burns were included in this study.The patients were randomly divided into two groups.The experimental group had 39 cases,who underwent the application of anterior chamber puncture and pH value measurement combined with routine treatment.Control group had 39 cases who were treated only with conventional combined therapy.Corneal edema duration time,visual acuity,the corneal neovascularization and other complications were observed.· RESULTS:Corneal edema duration time,visual acuity,the corneal neovascularization and other complications were compared between the experimental group and control group,and the difference had statistical significance(P<0.05).· CONCLUSION:The anterior chamber puncture and the pH measurement play an active role in the treatment of moderate ocular alkali burns.·