AIM:To investigate the diagnonsis effect of optical coherence tomography (OCT),standard automatic permetry (SAP) in the early glaucoma. ·METHODS:Forty-two patients 68 eyes with glaucoma (binoculus/ ocellanae:25/18,male/female:29/13,left/right:32/36,open/close:18/50) aged 36-82 years old,the average age was 60.8±0.92. Visual disks C/D and retinal nerve fibers layer thickness were inspected by automatic vision inspection and OCT scanners. ·RESULTS:The positive rate of diagnonsis of automatic vision inspection and OCT was 84.37% and 93.75%,respectively. The positive rate of inspection in OCT was higher than that of automatic vision inspection for early glaucoma patients. ·CONCLUSION:For glaucoma patient,the loss of retinal nerve fibers is earlier than the change in field of vision defects. Combined of visual field and OCT method can qualitatively and quantitatively get an objective assessment for vision defects of glaucoma.