·AIM:To investigate the effect of nursing intervention on the compliance of amblyopia therapy in children with congenital cataract,and the effect of compliance on therapeutic efficacy.·METHODS:Children with congenital cataract were randomly divided into two groups.Control group was given regular nursing care while intervention group was treated with nursing intervention therapy.The difference of compliance and efficacy between the two groups were compare and the correlation between nursing intervention and compliance and between compliance and therapeutic efficacy were analyzed.·RESULTS:Compared with control group,nursing intervention could significantly improve the compliance(P<0.05),and compliance was significantly correlated with therapeutic efficacy(P<0.01).·CONCLUSION:Nursing intervention can significantly improve the compliance of amblyopia therapy in children with congenital cataract,thus improve the therapeutic efficacy and the living quality of these children.·