Effect of ciliochoroidal detachment combined with implantation of silica gel buckling band on aqueous outflow in rabbits
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R779.6

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Science and Technology Research Project of Wuhan, China(No.200852199600); Innovation Research Fund of Huazhong University of Science and Technology, China(No.2010 JC027)

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    Abstract:

    AIM:To investigate the effect of ciliochoroidal detachment combined with implantation of silica gel buckling band on aqueous outflow in rabbit eyes.METHODS:Two groups were set up from 12 rabbits,experimental ciliochoroidal detachment combined with implantation of silica gel buckling band was performed on 6 rabbits’ right eyes,each eye of the other 6 rabbits received trabeculectomy as control.At 10,21,42 days postoperatively,the intraocular pressure,coefficient of aqueous outflow facility(C-value) were observed.RESULTS:Ten days postoperatively,IOP decrease percentage was consistent between experimental ciliochoroidal detachment combined with implantation of silica gel buckling band group(33.7±3.7)% and trabeculectomy group(32.2%±3.8%,P=0.501).At postoperative day 21,in experimental group,IOP decrease percentage was(14.7±1.6)%,which was larger than that in trabeculectomy group(2.3%±9.1%,P=0.013),IOP returned to normal at 6th week postoperatively in experimental group,while at 21st day postoperatively in trabeculectomy group.At 10th day postoperatively,C-value was 0.38±0.03 in experimental group and 0.35±0.03 in trabeculectomy group(P=0.16),at 21st day postoperatively,it was 0.26±0.03 and 0.21±0.02(P=0.006),and at 6th week postoperatively,it was 0.18±0.02 and 0.19±0.03 respectively(P=0.765).CONCLUSION:Ciliochoroidal detachment combined with implantation of silica gel buckling band could effectively reduce IOP of rabbits,increase the C-value,and enhance the uveoscleral outflow.

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Zhi-Qi Chen, Jing Gao, Gui-Gang Li, et al. Effect of ciliochoroidal detachment combined with implantation of silica gel buckling band on aqueous outflow in rabbits. Guoji Yanke Zazhi( Int Eye Sci) 2011;11(2):232-234

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