·AIM:To approach the method and skill of filtering operation for glaucoma under high intraocular pressure(IOP)and observe the curative effect.METHODS:All of 50 glaucoma patients with high IOP which was >40mmHg preoperatively.Trabeculectomy combined with peripheral iridectomy were performed in anterior chamber to decompress using MMC(0.2g/L or 0.4g/L)under scleral flap and fascia during operation.RESULTS:Followed-up for 3 months after operation,vision was improved in 26 cases,unchanged in 24 cases;IOP of 41 cases was <21mmHg;1 case received anterior vitrectomy and anterior chamber plastic operation because of occurring shallow anterior chamber at 1 week postoperatively;extraction of cataract,posterior capsule split and anterior chamber plastic operation were performed in 1 case;at 2 months postoperatively,2 cases received cyclophotocoagulation;IOP rised in 5 cases after 1 month,IOP was controlled under 21mmHg when they took 1-2 species hypotensive drugs.CONCLUSION:It is necessary to improve the filtering operation for success rate in glaucoma under high IOP.