AIM:To compare the effect of retinal cryocoagulation and cyclocryotherapy and trabeculectomy with the effect of retinal cryocoagulation and cyclocryotherapy and panretinal photocoagulation for neovascular glaucoma.METHODS:We retrospectively analyzed 69 cases 71 eyes from January 2006 to April 2010 in the First Hospital of China Medical University.37 cases 37 eyes were treated with retinal cryocoagulation and cyclocryotherapy and trabeculectomy,32 cases 34 eyes were treated with retinal cryocoagulation and cyclocryotherapy and panretinal photocoagulation.Visual acuity,intraocular pressure,the degradation of iris neovascularization and complications were observed before and after treatment.RESULTS:Visual acuity,intraocular pressure,the degradation of iris neovascularization and complications of the two groups were significantly different between before and after treatment.But the complications of panretinal photocoagulation group were significantly fewer than trabeculectomy group.CONCLUSION:The two methods have significant effects for neovascular glaucoma,but panretinal photocoagulation group has a lower incidence of postoperative complications.