AIM:To observe and discuss the value of using computer-aided imaging technology of binocular indirect ophthalmoscopy in laser photocoagulation treatment for retinopathy of prematurity(ROP).METHODS:The clinical data of 58 patients 116 eyes with threshold ROP or prethreshold type I ROP were retrospectively analyzed.Ocular fundus was examined by computer-aided imaging technology of binocular indirect ophthalmoscopy before and after in every operation.Before operation results were used to design the surgery;in operation results were used to detect the missed area after laser photocoagulation,after operation results were for the operation effect recording.The surgery was implemented under surface anesthesia with electrocardio monitoring.The follow-up duration was 3-12 months.RESULTS:Missed area was found in thirty-six eyes(31.0%)by computer-aided imaging technology of binocular indirect ophthalmoscopy of laser photocoagulation.The missed area was at once supplemented during surgery.All the eyes which had undergone one time laser photocoagulation had good result after surgery and the disease was controlled.At the end of follow-up duration,there was no unfavorable retinal structural outcome.CONCLUSION:Computer-aided imaging technology of binocular indirect ophthalmoscopy of laser photocoagula-tion for ROP can find missed area effectively during the operation.Second-time surgery was avoided by supplement laser photocoagulation in time.