AIM:To evaluate visual quality and the quality of life in patients after the implantation of the apodized diffractive Acrysof ReSTOR multifocal intraocular lens(IOL).METHODS:Sixty-seven patients (70 eyes) with age-related cataract were divided into two groups.Thirty cases (33 eyes) were performed with phacoemulsification and implanted with the apodized diffractive Acrysof ReSTOR multifocal intraocular lens (MIOL), and the other 37 cases (37 eyes)were implanted with AcrySof Natrural monofocal intraocular lens (SIOL).The uncorrected distance and near visual acuity, best distance and near visual acuity and intermediate uncorrected visual acuity were examined after surgery in all patients. Contrast sensitivity function was tested. The quality of life was observed by questionnaire at 3 months and 1 year. RESULTS:There was no significant difference between the two groups about the uncorrected,the corrected distance and near visions(P>0.05),while the postoperative near visual visions without corrected in the multifocal group was significantly better than that in the monofocal group (P<0.05).There was no significant difference in the multifocal group at 1 year and 3 months. Contrast sensitivity of eyes with MIOL was lower than that with SIOL. The spectacle independence in MIOL and SIOL groups were 83% and 32%. Intermediate uncorrected visual acuity in MIOL group was better than that in SIOL group. There were four patients complained with halo. Patients in MIOL group were satisfied with the better near visual acuity. CONCLUSION: The apodized diffractive Acrysof ReSTOR multifocal IOL may provide excellent full range of vision and higher percentage of spectacle independence, then improved quality of life for patients after phacoemulsification.