Reticular pseudodrusen(RPD) is different from typical drusen and has close relation with macular diseases. RPD may be a high-risk factor for age-related macular degeneration (AMD) development including geographic atrophy (GA) and choroidal neovascularization (CNV). So we must pay close attention to elderly. RPD has different images when different image methods are used, autofluorescent (AF) and infrared (IR) possess special value.