AIM:To investigate the clinical manifestations and therapy of patients suffering from corneal endotheliitis after PHACO cataract surgery.METHODS: Eleven cases (11 eyes) after PHACO cataract surgery were diagnosed with corneal endotheliitis according to the clinical manifestations. Antiviral agents and corticosteroids were used. All cases were observed and followed up.RESULTS: All the eleven cases were cured through treatment. The follow-up results showed no recurrence in 6 months.CONCLUSION: The topically and systemically use of enough antiviral agents and high-dose corticosteroids is effective in corneal endotheliitis. Early detection and treatment are the most important.