AIM:To investigate the treatments of epithelial ingrowth(EI)after laser in situ keratomileusis (LASIK),analyse the related factors,and evaluate efficacy of the treatment.METHODS:Ten patients (16 eyes) with EI were analyzed from 2666 paients(5212 eyes) who underwent LASIK from September 2006 to November 2011 in our hospital.The reason for occurrence of EI aftere LASIK was analyzed,the different treatment methods were used,and their efficacy was evaluated.RESULTS:The incidence rate of EI was 0.31% in 2666 paients(5212 eyes);According to the occurrence reasons,the occurrence time,the range and position,the different treatment methods were used.Four paients(5 eyes)were treated with 10g/L Prednisolone Acetate Ophthalmic Solution (Pred Forte)and intraocular pressure-lowering ophthalmic solution,EI disappeared;other six paients (11 eyes)were treated with pharmaceutical and surgery.The EI were cleaned up,and the corneal flap was dried in the open air for 1minute after repositioning the flap,and contact lens were used for 1-2 days after surgery.They were treated with Pred Forte and intraocular pressure-lowering ophthalmic solution after surgery.All paients had good visual acuity and no recurrence occured in the six months to four years follow-up.CONCLUSION:EI after LASIK is an special complication.Excluding contraindication preoperatively,operating normatively,early diagnosis and active treatment are effective treatment methods for EI.