Home > Archive>Volume 12, Issue 3, 2012 >447-450. DOI:10.3969/j.issn.1672-5123.2012.03.21
PDF HTML XML Export Cite reminder
Research status of dendritic cells in corneal diseases
Author:
  • Article
    • | |
  • Metrics
    • |
  • Reference [37]
    • |
  • Related [20]
    • | | |
  • Comments
    Abstract:

    Dendritic cells （DC）are the most efficient antigen- presenting cells which initiate immune responses. The corneal DC play a critical role in corneal transplantation rejection．Its maturation and centripetal migration strongly associated with the cornea transplantation and all types of keratitis. This article reviews the research on corneal DC and its role in corneal diseases.

    Reference
    1 Inaba K，inaba M，Romani N, et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemental with granulocyte/macrophage colony-stimulation factors. J Exp Med 1992;176（6）:1693-1702
    2赵勇.移植免疫耐受.北京：中国医药科技出版社2002:85-104
    3 Yamagami S, Yokoo S, Usui T, et al. Distinct populations of dendritic cells in the normal human donor corneal epithelium. Invest Ophthalmol Vis Sci 2005;46(12):4489-4494
    4 Niederkorn JY, Ross JR, He Y. Effect of donor Langerhans cells on corneal graft rejection. J Invest Dermatol 1992;99(5):104-106
    5 Hattori Ｔ, Chauhan ＳＫ, Lee Ｈ, et al. Characterization of langerin-expressing dendritic cell subsets in the normal cornea. Invest Ophthalmol Vis Sci 2011;52（7）:4598-4604
    6 Zhivov A, Stave J, Vollmar B, et al. In vivo confocal microscopic evaluation of Langerhans cell density and distribution in the normal human corneal epithelium. Graefes Arch Clin Exp Ophthalmol 2005;243(10): 1056-1061
    7 Mayer WJ, Irschick UM, Moser P, et al. Characterization of antigen- presenting cells in fresh and cultured human corneas using novel dendritic cell markers. Invest Ophthalmol Vis Sci 2007;48(10):4459-4467
    8 Gao N, Yin J, Yoon GS, et al. Dendritic cell-epithelium interplay is a determinant factor for corneal epithelial wound repair. Am J Pathol 2011;179(5):2243-2253
    9 Yamagami S, Ebihara N, Usui T, et al. Bone marrow-derived cells in normal human corneal stroma. Arch Ophthalmol 2006;124(1):62-69
    10 Hamrah P, Liu Y, Zhang Q, et al. The corneal stroma is endowed with a significant number of resident dendritic cells. Invest Ophthalmol Vis Sci 2003;44(2):581-589
    11 Resch MD, Imre L, Tapaszto B, et al. Confocal microscopic evidence of increased Langerhans cell activity after corneal metal foreign body removal. Eur J Ophthalmol 2008;18(5):703-707
    12 Su PY, Hu FR, Chen YM, et al. Dendritiform cells found in central cornea by in vivo confocal microscopy in a patient with mixed bacterial keratitis. Ocul Immunol Inflamm 2006;14(4):241-244
    13 Lee EJ, Rosenbaum JT, Planck SR. Epifluorescence intravital microscopy of murine Corneal dendritic cells. Invest Ophthalmol Vis Sci 2010;51（４）:2101-2108
    14 Mastropasqua L, Nubile M, Lanzini M, et al. Epithelial dendritic cell distribution in normal and inflamed human cornea: in vivo confocal microscopy study. Am J Ophthalmol 2006;142(5):736-744
    15 Hamrah P, Liu Y, Zhang Q, et al. Alterations in corneal stromal dendritic cell phenotype and distribution in inflammation. Arch Ophthalmol 2003;121(8):1132-1140
    16 Shen LL, Barabino Ｓ, Andrew W, et al. Effect of the ocular microenvironment in regulating corneal dendritic cell maturation. Arch Ophthalmol 2007;125(7):908-915
    17 Perez VL, Rodriguez-Perez JP, CarlsonIn EC, et al. In vivo visualization of early inflammatory cell recruitment in corneal transplantation using MAFIA and EGFP-chimeric mice. Invest Ophthalmol Vis Sci 2004；45（10）: 4523-4529
    18 Dekaris I, Gabric N, Markotic A. TNF-α and IL-1 Production by ｄiseased ｈuman ｃorneas. Invest Ophthalmol Vis Sci 2003；44（５）:668-672
    19 Turhan A, Schrems WA, Mantopoulos D, et al. Dendritic cell recruitment to the cornea is differentially regulated in steady state and inflammation. Invest Ophthalmol Vis Sci 2011;52（２）: 1115-1121
    20 Hong J, Zheng T, Xu J, et al. Assessment of limbus and central cornea in patients with keratolimbal allograft transplantation using in vivo laser scanning confocal microscopy: an observational study. Graefes Arch Clin Exp Ophthalmol 2011;249(5):701-708
    21 Raimondi G, Thomson AW. Dendritic Cells, tolerance and therapy of organ allograft rejection. Contrib Nephrol 2005;146（１）:105-120
    22 Huq S, Liu Y, Benichou G, et al. Relevance of the direct pathw- ay of sensitization in corneal transplantation is dictated by the graft bed microenvironment. J Immunol 2004;173(7):4464-4469
    23 Yamagami S, Dana MR, Tsuru T. Draining lymph nodes play an essential role in alloimmunity generated in response to high-risk corneal transplantation. Cornea 2002;21(4):405-409
    24 Yamagami S, Amano S. Role of resident corneal leukocytes and draining cervical lymph nodes in corneal allograft rejection. Cornea 2003;22( 7Suppl):61-65
    25 Fu H, Larkin DF, George AJ. Immune modulation in corneal transplantation. Transplant Rev( Or lando) 2008;22(2):105-115
    26 Hazlett LD, McClellan SA, Rudner XL. The role of langerhans cells in pseudomonas aeruginosa infection. Invest Ophthalmol Vis Sci 2002;43（１）:189-196
    27 Alsuhaibani AH, Sutphin JE, Wagoner MD. Confocal microscopy of subepithelial infiltrates occurring after epidemic keratoconjunctivitis. Cornea 2006;25(7):778-780
    28 Dosso ＡＡ, Rungger-Brandle E. Clinical course of epidemic keratoconjunctivitis evaluation by in vivo confocal microscopy. Cornea 2008;27(3):263-268 29 Miller JK, Laycock KA, Nash MM, et al. Corneal langerhans cell dynamics after herpes simplex virus reactivation. Invest Ophthalmol Vis Sci 1993;34（７）:2282-2288
    30 Frank GM，Buela KG，Maker DM, et al. Early responding dendritic cells direct the local NK response to control herpes simplex virus 1 infection within the cornea. J Immunol 2012;188(2):1350-1359
    31 Cruzat Ａ, Witkin Ｄ, Baniasadi Ｎ, et al. Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis. Invest Ophthalmol Vis Sci 2011;52（８）:5136-5143
    32 Cruzat Ａ, Schrems ＷＡ, Hoesｌ ＬＭ, et al. Contralateral clinically unaffected eyes of patients with unilateral infectious keratitis demonstrate subclinical diminishment of corneal nerves and increase in dendritic cell density. Invest Ophthalmol Vis Sci 2011;52（２）:1206-1212 33 Cruzat A, Zheng L, Lee H,et al. Diminishment of the subbasal corneal nerve plexus is associated with increased density of epithelial dendritic cells: an in vivo confocal microscopy study in patients with infectious keratitis. Invest Ophthalmol Vis Sci 2010;51（６）:2878-2883 34 Kurbanyan Ｋ, Deng Ｓ. In vivo confocal microscopy study of dendritic cell counts in corneal limbal stem cell deficiency. Invest Ophthalmol Vis Sci 2011;52（８）:5117-5123
    35 Ceresara G, Fogagnolo P, Cilla SD, et al. Corneal involvement in Crohn’s disease: an in vivo confocal microscopy study. Cornea 2011;30(2):136-142
    36 Wang Y, Zhao F, Zhu W, et al. In vivo confocal microscopic evaluation of morphologic changes and dendritic cell distribution in pterygium. J Ophthalmol 2010;150(5):650-655
    37 Eden Ｕ, Fagerholm Ｐ, Lagali ＮＳ. Pathologic epithelium and anterior corneal nerves in congenital Aniridic Keratopathy. Invest Ophthalmol Vis Sci 2011;52（１）:292-298
    38 Sacchi M, Carini E, Mattioli S. Corneal involvement after 23-gauge vitrectomy with silicone oil endotamponade for retinal detachment: An in vivo confocal microscopy study. Invest Ophthalmol Vis Sci 2010;51（7）:3790-3798
    39 Qazi Ｙ, Cruzat Ａ, Baniasadi Ｎ. Early effects of contact lens wear on immune cell density of the ocular surface: preliminary results of a laser in vivo confocal microscopy study. Invest Ophthalmol Vis Sci 2011; 52（１０）:6551-6558
    40 Sankaridurg PR, Rao GN, Rao HN, et al. AT Pase-positive dendritic cells in the limbal and corneal epithelium of guinea pigs after extended wear of hydrogel lenses. Cornea 2000;19(3):374-377·
    Cited by
    Comments
    Comments
    分享到微博
    Submit
Get Citation

Yan Fu, Xiao-Wei Gao. ,/et al.Research status of dendritic cells in corneal diseases. Guoji Yanke Zazhi( Int Eye Sci) 2012;12(3):447-450

Copy
Share
Article Metrics
  • Abstract:1761
  • PDF: 1498
  • HTML: 0
  • Cited by: 0
Publication History
  • Received:January 17,2012
  • Revised:February 12,2012
You are the 26444 Visitors
Governing Body：Department of Health, Provincial Government of Shaanxi, China
Organizer：Xi'an Medical Association of China
Address：Room 11707-08, Building 2, Unit 1, Wanda Plaza, No.8 Yanta North Road, Xi'an 710054, Shaanxi Province, China
Fax：(8629)82245172 Phone：(+8629)82245172/82210956
Email：ijopress@163.com
® 2025 All Rights Reserved   The terms of CC BY-NC-ND 4.0 are applicable to all open access content.