AIM:To observe the combined curative effect of early panretinal photocoagulation (PRP) and compound anisodine para-temporal-superficial artery injection for radiation retinopathy（RR）. METHODS:Twenty-one patients (41 eyes ) with RR in our hospital received early PRP and compound anisodine para-temporal-superficial artery injection. The visual acuity, capillary nonperfusion, retina-neovascularization, and complications at 3 months after treatment were observed. RESULTS:Three months after the treatment, visual acuity were increased in 6 eyes (14.6%) , steady in 31 eyes (75.7%) , decreased in 4 eyes (9.7%) . Iridal neovascularization regressed in 2 eyes, while the other one received the cyclophotocoagulation. Primary retinal neovascularization regressed in 9 eyes (75%), and primary retinal nonperfusion disappeared in 22 eyes (687%), primary retinal nonperfusion shrinked more than five disc area in 7 eyes (21.8%), the total effective rate was 90. 5%. Only one eye developed vitreous hemorrhage,however, no optic disc and iridal neovascularization, and neovascular glaucoma were observed; no complication related with the treatment appeared in all patients. CONCLUSION:Early PRP and compound anisodine para-temporal-superficial artery injection is effective and reasonable integrated traditional and western medicine treatment for radiation retinopathy.