AIM:To observe the application efficacy of deproteinized calf blood extract eye gel for postoperative recurrent pterygium corneal incision repair. METHODS:Totally 68 cases(68 eyes) of postoperative recurrent pterygium corneal incision edema were randomly divided into 2 groups with 34 cases(34 eyes) in each group. The control group used routine diclofenac sodium eye drops plus antibiotics eye drops and simultaneous bFGF eye drops alternately, four times a day. The treatment group used deproteinized calf blood extract eye gel 4 times a day in addition to the daily alternate application of diclofenac sodium eye drops plus antibiotics eye drops. The course of treatment was 1 month. Contrast analysis was conducted on the subjective symptoms, signs, and repair of corneal incision in patients before and 3, 7, 14days, 1 month after treatment respectively. RESULTS:About 3, 7, 14days after recurrent pterygium surgery, corneal incision edema weakened more significantly, incision repaired faster, and subjective symptoms subsided in a shorter time in treatment group than in control group. 1 month after operation, there was no significant difference between the two groups. CONCLUSION:Deproteinized calf blood extract eye gel has a shorter onset time, better comfort and safety for the early repair of postoperative recurrent pterygium corneal incision, and can reduce the incidence of postoperative infectious keratopathy and postoperative corneal astigmatism with good effect.