Therapeutic effect of selective laser trabeculoplasty on steroid-induced glaucoma
Author:
Fund Project:

中国国家自然科学基金资助项目(No.81000402)

  • Article
  • | |
  • Metrics
  • |
  • Reference [6]
  • |
  • Related [20]
  • | | |
  • Comments
    Abstract:

    AIM:To report the therapeutic effect of selective laser trabeculoplasty (SLT) on steroid-induced glaucoma. METHODS:This study was made on 8 eyes of 8 cases who received SLT for glaucoma secondary to treatment with peroral corticosteroid. The series comprised 5 males and 3 females. The age ranged from 55 to 74 years, average 65 years. Corticosteroid had been prescribed for 11.5±3.3 years. Intraocular pressure (IOP) started to rise after 6.2±2.9 years of treatment. Each case had been treated with 2.9±0.5 topical drugs for glaucoma. Patients had been treated with topical medications and systemic corticosteroid after SLT. RESULTS:IOP averaged 26.8±5.1mmHg before SLT, 202±3.2mmHg after 1 month, 17.6±2.2mmHg after 3 months, and 16.1±1.4mmHg after 6 months. Each postoperative IOP was significantly lower than preoperative one. CONCLUSION:SLT was effective for glaucoma secondary to systemic corticosteroid in the present series.

    Reference
    1王秋燕,胡竹林.选择性激光小梁成形术治疗开角型青光眼的研究进展.国际眼科杂志2011;11(5):828-829
    2 Clark AF, Wilson K, McCartney MD,et al.Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells.Invest Ophthalmol Vis Sci 1994;35(1):281-294
    3 Francois J. The importance of mucopolysaccharides in intraocular pressure regulation.Invest Ophthalmol Vis Sci 1975;14(3):173-176
    4 Zhou L, Li Y, Yue BY. Glucocorticoid effects on extracellular matrix proteins and integrins in bovine trabecular meshwork cells in relation to glaucoma.Int J Mol Med 1998;1(2):339-346
    5 el-Shabrawi Y, Eckhardt M, Berghold A, et al.Synthesis pattern of matrix metalloproteinases (MMPs) and inhibitors (TIMPs) in human explant organ cultures after treatment with latanoprost and dexamethasone.Eye2000;14(Pt 3A): 375-383
    6 Pizzimenti JJ, Nickerson MM, Pizzimenti CE, et al.Selective laser trabeculoplasty for intraocular pressure elevation after intravitreal triamcinolone acetonide injection.Optom Vis Sci 2006;83(7):421-425
    Cited by
    Comments
    Comments
    分享到微博
    Submit
Get Citation

Yu Zhao, Chun-Xia Wang, Jun Xu,/et al.Therapeutic effect of selective laser trabeculoplasty on steroid-induced glaucoma. Guoji Yanke Zazhi( Int Eye Sci) 2012;12(5):963-964

Copy
Share
Article Metrics
  • Abstract:1624
  • PDF: 1606
  • HTML: 0
  • Cited by: 0
Publication History
  • Received:February 08,2012
  • Revised:March 21,2012