AIM: To observe the efficacy of citicoline sodium on glaucoma visual field damage.

METHODS: Glaucoma patients with visual field defects and intraocular pressure(IOP)< 18mmHg were chosen, totally 29 patients 48 eyes were selected, of which 16 cases were male, 27 eyes, 13 cases were female, 21 eyes; in which 25 eyes were with primary open-angle glaucoma; 19 eyes with angle-closed glaucoma, and 4 eyes with normal IOP glaucoma. Citicoline sodium tablets were used orally, each 0.2g 3 times daily, continuously for three months. The visual field mean defect(MD), mean sensitivity(MS)and loss variance(LV), and other indicators were detected before and 1 month, 3 months after treatment.

RESULTS: One month after treatment, the MS of 48 eyes was significantly higher than that before treatment, the difference was statistically significant(P<0.01); MD value was significantly lower than that before treatment, the difference was statistically significant(P<0.05). Three months after treatment, the MS of patients was significantly higher than that before treatment, the difference was statistically significant(P<0.01); MD and LV value decreased, the difference was statistically significant(P<0.01).

CONCLUSION: Citicoline sodium has protective effect on visual function of primary glaucoma to some extent.