AIM: To evaluate the efficacy and safety of Toric implantable collamer lens(TICL)for high myopia with astigmatism.

METHODS: This retrospective case series included 40 eyes of 22 patients from February 2010 to June 2011. A TICL was intraocularly implanted via a 3mm clear corneal incision after local anesthesia.Patients were examined preoperatively and followed-up 1 day, 1 week, 1 month, 3, 12 months postoperatively for uncorrected visual acuity. The examinations also included best-corrected visual acuity(BCVA)preoperatively, slit-lamp examination, refraction, intraocular pressure, endothelial cell morphometry, cylinder axis of the TICL, etc.

RESULTS: The uncorrected visual acuity in 40 eyes was equal or improved after 3 months of the operation in comparison with BCVA of preoperation. The spherical refraction after operation was within(-0.5- +0.5)D. The cylinder refraction was within(-0.75-0)D. The axial deviation of TICL after 1 month postoperatively within 10° was 95.0%(38/40). The axial deviation of TICL between 10 ° and 15° was 2.5%(1/40). The axial deviation of TICL above 30° was 2.5%(1/40)whose astigmatic axial rotation was changed after surgical intervention. As a result, the axial deviation of TICL was within 10 degrees. 7 eyes had increased intraocular pressure shortly after surgery and after treatment the intraocular pressure became normal in 1 week. No severe complications including secondary glaucoma and cataract and etc occurred.

CONCLUSION: TICL implantation appears to be an effective, safe method for high myopia with astigmatism.