AIM: To explore the reasons and management of reoperation after vitrectomy for proliferative diabetic retinopathy(PDR)which need more times surgery.

METHODS:The cases with PDR which need more times surgery after vitrectomy were retrospectively analyzed in 3 years.

RESULTS: Twenty-six eyes(13.8%)of 24 cases needed more times surgery in 189 eyes. Of those 26 eyes, 3 eyes had vitreous hemorrhage again, 1 eye had hyphema, 11 eyes(5.8%, 3 eyes accompanied by neovascular glaucoma)had retinal detachment which occupied 42.3% of reoperation eyes, 6 eyes(3.2%)had cataract extraction, 5 eyes had pure silicon oil removing. 6 eyes(3.2%)of 189 eyes happened neovascular glaucoma. Every glaucoma eye accompanied by cataract extraction. 19 eyes had two times surgery, 7 eyes had three or more operations(5 eyes combining with retinal detachment).

CONCLUSION:Retinal detachment is the main cause for the reoperation after vitrectomy for PDR. Three or more times surgery may be needed if retinal detachment occurred after vitrectomy. It is worth paying more attention to neovascular glaucoma. Appearing retinal detachment must be on the alert and cataract extraction must be careful.