AIM:To observe the clinical curative effect of povidone iodine combined with carbolic acid in the treatment of fungal corneal ulcer.

METHODS: A total of 110 eyes clinically diagnosed with fungous cornea ulcer were divided to two groups at random, each with 55 eyes. The observation group was firstly treated with povidone iodine eye drops, carbol cauterize corneal ulcer and then, Fluconazole eye ointment and recombinant bovine basic fibroblast growth factor gel enveloping eyes. The control group was firstly treated with iodine tincture cauterize corneal ulcer and then used Fluconazole eye ointment and recombinant bovine basic fibroblast growth factor gel enveloping eyes. The clinical feasibility of iodine tincture and povidone iodine combined with carbolic acid in the treatment of fungal corneal ulcer was observed and comparatively studied.

RESULTS: Fifty-five eyes in the observation group used povidone iodine combined with carbolic acid cauterize corneal ulcer wound surface, all ulcer healed up, and the course of disease was shortened, the effect was better than the control group(P<0.05).

CONCLUSION:Povidone iodine combined with carbolic cauterize in the treatment of fungal corneal ulcer can enhance the curative rate obviously. It is an effective and safe therapeutic method.