AIM:To evaluate the effect of comprehensive treatment for children and teenagers with anisometropia amblyopia.

METHODS: Forty-five children and teenagers with anisometropia amblyopia, aged 8-15 years old, selected from our hospital between January 2007 and October 2010, were divided into two groups. Group A(22 patients)wore rigid gas permeable(RGP)lenses and group B wore eyeglass frames. Both groups received same amblyopia therapy with a patch, red light flashing, synoptophore disinhibition, and using of oral levodopa and depending on binocular vision and stereopsis comprehensive treatment method to carry on the treatment. Follow-up for 30 months observed in patients with visual acuity and stereopsis of near and far.

RESULTS: Comprehensive treatment of amblyopia after 30 months, two cases of corrected visual acuity were improved, Recovery rates were different for groups A and B:40.9%(9/22)and 17.4%(4/21), the curative effect of group A was significantly higher in B group, two groups had statistical significance(χ²=6.932, P<0.05). The rank sum test, group A of far and near stereopsis was clearly higher than group B(P<0.05).

CONCLUSION:Older children and teenagers with anisometropic amblyopia should take active treatment of amblyopia. For anisometropic amblyopia, patients should be recommended to wear RGP lens, which can improve the clinical cure rate,and maximize the possible recovery of binocular vision.