AIM:To investigate the cause of happening and comprehensive treatment of children's frequent eye blink.

METHODS: A series of examination were performed in 73 children with frequent eye blink. They were asked about history in detail, visual acuity, position of eye, slit-lamp microscope, fluorescent, tear film break-up time(BUT), Schirmer Ⅰ test, ocular funds, mydriasis optometry check on children under the vision, and the patients levels of serum lead(Pb), cadmium(Cd), calcium(Ca), iron(Fe), zine(Zn), copper(Cu), magnesium(Mg)7 trace elements were measured.

RESULTS: The cause of frequent instantaneous purpose of the 73 cases of children: the ocular surface and ocular adnexal disease, unhealthy living habits, stability of the tear film, ametropia, serum trace elements lack and so on.

CONCLUSION:Frequent eye blink in children is a common and frequently occurring disease, but it can be easily overlooked. Due to eye disease, physiology, medicine, environment and other factors affect, Its cause is more complex, multiple etiological factor simultaneous with one case. Correct analysis of the reasons for choosing an effective treatment can significantly relieve symptoms and improve the clinical cure rate.