AIM: To investigate the therapeutic effects of transscleral cyclophotocoagulation procedures(TCP)with 810nm laser for refractory glaucoma.

METHODS: Totally 25 patients(30 eyes)with refractory glaucoma were treated with TCP. The follow-up time was 3 months, the patients' symptom, intraocular pressure(IOP), visual acuity and complications were analyzed.

RESULTS: During the follow-up period, all patients' ocular pain was reduced. The mean IOP before TCP and at the last follow-up time were(50.42±2.50)mmHg(1kPa=7.5mmHg)and(15. 95±4.19)mmHg, respectively, the IOP decreased after TCP, there was significant difference(P<0.001). After TCP, the visual acuity improved in 2 eyes(6.7%), had no change in 24 eyes(80.0%), decreased in 4 eyes(13.3%). After TCP, the exudation of anterior chamber appeared in 12 eyes(40.0%), hyphema of anterior chamber appeared in 3 eyes(10.0%), vitreous hemorrhage in 1 eye(3.3%), which were all cured after drug treatment.

CONCLUSION: TCP with 810nm laser in treatment of refractory glaucoma has curative effect, can degrade the IOP, lessen ocular pain and with few complications.