AIM: To study the clinical curative effect and securityof autologous front plate layer sclera edge transplantation in treatment of corneal peripheral small area severe alkali burn.

METHODS:Totally 39 cases(39 eyes)with corneal peripheral small area severe alkali burn were included, they underwent local debridement, excision of infection at the front plate layer of corneal and adjacent lamellar sclera, also part of the conjunctiva, the front plate layer sclera and conjunctival in the corresponding health eye was taken and transplanted. Patients' postoperative subjective symptoms(pain, photophobia, and tears), vision, corneal epithelium time to repair and recurrence, the healthy eye eyesight, healing and sequel were observed.

RESULTS:After postoperative follow-up of 2-12 months, all patients' corneal epithelium healed, patients subjective symptoms rapidly recovered, no vision loss occurred, no relapse. Health canthus sclera edge wound healing was good, without sequela.

CONCLUSION:Autologous front plate sclera transplantation in the treatment of corneal peripheral small area severe alkali burn, the operation is simple, which can effectively shorten the corneal alkali burn healing time, promote corneal epithelium repair, health eyes(donor eyes)good recovery, without sequelae.