AIM: To observe the effect ofvitreoretinal surgery for late state of proliferative diabetic retinopathy(PDR).

METHODS: Totally 38 cases(45 eyes)with PDR stageⅥ operated with standard vitreoretinal surgery were analyzed retrospectively. Preoperative and postoperative visual acuity was studied. The complications of post-operation were analyzed.

RESULTS: Forty-five eyes were followed-up in the find examination. The vision of 0.05 or better was obtained from 14/45 eyes(31.1%)to 30/45 eyes(66.7%), in which, 22/30 eyes(73.3%)were 0.1 or better. The major operative complications included highintraocular pressure, vitreous hemorrhage, retinal detachment, complicated cataract, neovascular glaucoma, optic atrophy and ocular-atrophy.

CONCLUSION:Vitreoretinal surgery is an effective and safe procedure for the late stage of PDR to master surgical indications and techniques in order to obtain better visual improvement and reduce the surgical complications.