AIM:To investigate the efficacy of intravitreal lucentis combined laser photocoagulation treatment on macular edema.

METHODS: Ninety –eight patients(136 eyes)with macular edema diagnosed by ocular-fundus examination, fundus fluorescein angiography(FFA). Sixty-eight eyes of them were treated with intravitreal lucentis combined laser photocoagulation and sixty-eight eyes only laser photocoagulation. The follow-up time was 1 month, 3, 6 months. Visual acuity and FFA were measured.

RESULTS: Among patients with intravitreal lucentis combined laser photocoagulation, visual acuity in 51 eyes(75.0%)was improved in 2 lines or more and 10 eyes(14.7%)remained no change, 7 eyes(10.3%)deceresed. Edema in 59 eyes(86.8%)reduced after treament. Among patients with laser photocoagulation, visual acuity in 12 eyes(17.6%)was improved in 2 lines or more and 42 eyes(61.8%)remained no change, 14 eyes(20.6%)deceresed. Edema in 21 eyes(30.9%)reduced after treatment.

CONCLUSION: The result of intravitreal lucentis acetonide combined laser photocoagulation treatment for macular edemae is better than those of only using laser photocoagulation.